Glucosense MR 60 Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Gliclazide

Indications/Uses

Type 2 NIDDM in adults when dietary measures, physical exercise & wt loss alone are insufficient to control blood glucose.

Click to view Glucosense MR 60 detailed prescribing information

Dosage/Direction for Use

Initially 30 mg daily, may be increased to 60, 90 or 120 mg daily in successive steps w/ at least 1 mth interval. Max: 120 mg daily. Switching from gliclazide 80 mg 1 tab gliclazide 80 mg is comparable to 1 tab gliclazide MR 60 mg. Switching from another oral antidiabetic agent Initially 30 mg daily.

Click to view Glucosense MR 60 detailed prescribing information

Overdosage

View Glucosense MR 60 overdosage for action to be taken in the event of an overdose.

Administration

Should be taken with food.

Contraindications

Hypersensitivity to gliclazide, other sulfonylureas or sulfonamides. Type 1 diabetes; diabetic pre-coma & coma, diabetic ketoacidosis. Concomitant use w/ miconazole. Severe renal or hepatic insufficiency. Lactation.

Click to view Glucosense MR 60 detailed prescribing information

Special Precautions

Hypoglycemia; malnutrition, irregular mealtimes, skipping meals, fasting or dietary changes, imbalance between physical exercise & carbohydrate intake, overdosage; certain endocrine disorders eg, thyroid disorders, hypopituitarism, adrenal insufficiency; dysglycemia. Regularly monitor blood glucose levels & glycated Hb levels. Galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption. Concomitant use w/ St. John's wort (Hypericum perforatum). Renal & severe hepatic insufficiency. Pregnancy. Elderly.

Click to view Glucosense MR 60 detailed prescribing information

Use In Pregnancy & Lactation

Click to view Glucosense MR 60 detailed prescribing information

Adverse Reactions

Hypoglycemia; GI disturbances eg, abdominal pain, nausea, vomiting, dyspepsia, diarrhoea, constipation.

Click to view Glucosense MR 60 detailed prescribing information

Drug Interactions

Increased risk of hypoglycemia w/ miconazole systemic/oromucosal gel, systemic phenylbutazone, alcohol. Potentiated blood glucose-lowering effect w/ other antidiabetic agents (eg, insulins, acarbose, metformin, thiazolidinediones, dipeptidyl peptidase-4 inhibitors, GLP-1 receptor agonists), β-blockers, fluconazole, ACE inhibitors (captopril, enalapril), H₂-antagonists, MAOIs, sulfonamides, clarithromycin, NSAIDs. Increased blood glucose levels w/ danazol, chlorpromazine, glucocorticoids, ritodrine, salbutamol, terbutaline IV, St. John's wort prep. Dysglycemia w/ fluoroquinolones, warfarin.

Click to view Glucosense MR 60 detailed prescribing information

Storage

View Glucosense MR 60 storage conditions for details to ensure optimal shelf-life.

Action

View Glucosense MR 60 mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Antidiabetic Agents

ATC Classification

A10BB09 - gliclazide ; Belongs to the class of sulfonylureas. Used in the treatment of diabetes.

Regulatory Classification

Presentation/Packing

Form

Glucosense MR tab 60 mg

Packing/Price

10 × 10's

Glucosense MR 60

gliclazide

Manufacturer:

Unison

Distributor:

Medispec